A Once Upon a Time in Hollywood reunion looks set to be on the cards, with reports emerging that Margot Robbie will replace Emma Stone in an upcoming movie starring Brad Pitt.

Emma Stone has been forced to bow out of period Hollywood drama Babylon due to scheduling reasons according to Deadline, with The Suicide Squad's Margot Robbie tipped to replace her alongside Pitt.

Babylon – which will be directed by La La Land's Damien Chazelle – has been in the works for over a year and is currently set for a late 2021, early 2022 release, just in time for the awards season.

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brad pitt, margot robbie and leonardo dicaprio
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Produced by Olivia Hamilton, Matt Plouffe, Marc Platt, and Tobey Maguire, the drama will follow the shifting landscape of Hollywood when the industry turned from silent film to so-called 'talkies'.

Aside from what we assume are intense behind-the-scenes negotiations, Margot Robbie has been busy teasing the upcoming Suicide Squad sequel from James Gunn, where she'll reprise her role as Harley Quinn.

Revealing an especially tough scene on The Suicide Squad set, Margot said: "I don't want to give it away. When you watch the movie, it's probably about halfway through. There's an insane sequence that Harley does which was one of the most difficult things I've ever shot on-screen.

margot robbie as harley quinn in suicide squad
Warner Bros.

"And we shot it in like four days and I remember looking at the schedule and being like 'Oh my god, we're not going to be able to do this. This is gonna be impossible.'"

We've got faith in you, Margot.

The Suicide Squad is currently due for release on August 6, 2021.

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Rianne Houghton is a freelance news writer at Digital Spy.