1Annabel Scholey as Charlotte
Karwai TangWho is Charlotte? Consultant cardiothoracic surgeon Charlotte is the beating heart of The Couple Next Door. The wife of Jacob and child-free by choice, Charlotte is competitive and respected at work. Her life, on the surface, is perfect until she begins to question if a life of domestic predictability is in fact what she wants. Her ex Leo's re-entry into the fray and Mia's emergence as a curious new figure ends up confronting Charlotte in ways she couldn't have expected.
What else has Annabel Scholey been in? Scholey gained acclaim when she starred in 2023's The Serial Killer's Wife, but her breakout role was in 2009 BBC drama Being Human.
2Sam Palladio as Jacob
Kate Green/BAFTAWho is Jacob? Consultant anaesthetist Jacob is both charming and confident. He loves his wife Charlotte dearly, but disguises his insecurities about his status so when Mia arrives, she proves a temptation that may well be too great to avoid..
What else has Sam Palladio been in? Palladio is an English actor and musician, best known for playing Gunnar Scott in the ABC musical drama Nashville. He also appeared in recurring roles in the sci-fi series Humans.
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3Aggy K. Adams as Mia
Stephane Cardinale - CorbisWho is Mia? Mia is the new surgical nurse at the hospital where Charlotte works. She's migrated from Norway to the UK and, as the name of the series would suggest, has moved into the house next door to Charlotte and Jacob. But all is not quite as it may seem with Mia..
What else has Aggy K. Adams been in? Adams is a British actor who's previously had roles in The Witcher and Oh, Ramona!.
4Sendhil Ramamurthy as Leo
getty imagesWho is Leo? After a whirlwind romance with Charlotte while the pair were studying at the same medical school, Leo travelled the world trying to shirk the wealthy life he'd been born into. Now, with an ailing father, he's back and seeing his long-lost love Charlotte again stirs up some confronting feelings.
What else has Sendhil Ramamurthy been in? Ramamurthy is an American actor who's previously starred in Heroes, Beauty and the Beast and Never Have I Ever.
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5Hugh Dennis as Alan
Tristan Fewings/BAFTAWho is Alan? While recovering from a stroke, Alan begins serving community service after his past with season one character Becka was exposed. Now isolated and alone, Hugh is left shunned by his community and wondering whether he'll truly change.
What else has Hugh Dennis been in? Dennis is a British comedian and actor who's previously starred in Fleabag, Nativity Rocks! and No Time to Die, among many others.
6Maimie McCoy as Gemma
Darren GerrishWho is Gemma? Charlotte's longtime best friend and a senior manager at the hospital, Gemma is still reeling from her divorce after her husband Ben left her for a younger woman. The point at which she meets Leo, however, changes dramatically. But with Leo's heart still very much with Charlotte, can Gemma manage to turn his head?
What else has Maimie McCoy been in? The British actor has previously had roles in ITV's reboot of Van der Valk and she starred as Milady de Winter in The Musketeers.
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7Adam James as Ben
Jemal CountessWho is Ben? Ben is the hospital medical director, making him ostensibly Jacob's boss. Also in the grips of a mid-life crisis, Ben left his wife Gemma for a younger gym receptionist, but as Gemma grows close to Leo, he starts to question his choices entirely.
What else has Adam James been in? British actor James has starred in all manner of films, and has also been a recurring character on Casualty.
8Tanya Moodie as Yvonne
Mike MarslandWho is Yvonne? Fellow nurse Yvonne is Mia's closest friend at the hospital. Known for keeping out of the hospital gossip and drama, Yvonne is loveable but unlucky in love, so when Mia suggests a potential match in Alan, her interest piques.
What else has Tanya Moodie been in? Moodie is a British-Canadian actor and producer who's best known for her roles in Motherland and Silo, as well as her esteemed stage work with the Royal Shakespeare Company and the National Theatre.

Naomi May is a seasoned culture journalist and editor with over ten years’ worth of experience in shaping stories and building digital communities. After graduating with a First Class Honours from City University's prestigious Journalism course, Naomi joined the Evening Standard, where she worked across both the newspaper and website. She is now the Digital Editor at ELLE Magazine and has written features for the likes of The Guardian, Vogue, Vice and Refinery29, among many others. Naomi is also the host of the ELLE Collective book club.
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